GEO series
Detecting chromatin accessibility changes that are dependent on ATF4 under mitochondrial stress
GSE242581
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
18 samples
2026/06/22
GPL24247
Summary
ATF4 is a stress-responsive gene which is critical for cell survival under stress conditions. ATF4 expression is upregulated under mitochondrial stress and the expression of a few chromatin remodelling genes are regulated by ATF4. ATAC-seq was performed on differentiated neurons after shATF4 knock-down under normal and mitochondrial stress conditions.
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