Targeting Lysine Demethylase 5 (KDM5) in Mantle Cell Lymphoma
RNA-seq (gene expression) · human · 36 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Mantle cell lymphomaThis series is part of our curated briefing on it.
- Samples
- 36 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243395_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1018417 and SRA study SRP461404. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 36 more — browse all 36 samples with per-sample file links →
- GSE273121 Ironomycin induces Mantle Cell Lymphoma cell death by targeting iron metabolism adicction 12 samples same disease briefing · shares targeting, lymphoma, mantle
- GSE271664 Functional Genomics and Tumor Microenvironment Analysis Reveal Prognostic Biological Subtypes in Mantle Cell Lymphoma [RNA-seq] 51 samples same disease briefing · shares lymphoma, mantle
- GSE303064 Gene expression profile at single cell level of primary and relapse mantle cell lymphoma (MCL) 20 samples same disease briefing · shares lymphoma, mantle
- GSE229517 Resistance to PRMT5-targeted therapy in mantle cell lymphoma 6 samples same disease briefing · shares lymphoma, mantle
- GSE327598 Cyclin-dependent kinase-9 and oxidative phosphorylation inhibition overcome ibrutinib resistance in mantle cell lymphoma 4 samples same disease briefing · shares lymphoma, mantle
- GSE305144 Transcriptional reprogramming in mantle cell lymphoma promotes BTK inhibitor resistance 63 samples same disease briefing · shares lymphoma, mantle
- GSE302906 CUT&RUN profiling of SOX11 and SMARCA4 in mantle cell lymphoma 32 samples same disease briefing · shares lymphoma, mantle
- GSE239353 CARD11 gain of function upregulates BCL2A1 and promotes resistance to targeted therapies combination in B-cell lymphoma 18 samples same disease briefing · shares lymphoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.