GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levels
RNA-seq (gene expression) · mouse · 19 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 19 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levelsDevelopmental cell · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243640_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1019318 and SRA study SRP462118. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 19 samples.
How we read this: 6 replicated groups read from 19 sample titles; they account for 19 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7792152 WT_myoblasts_1 WT_myoblasts
- GSM7792153 WT_myoblasts_2 WT_myoblasts
- GSM7792154 WT_myoblasts_3 WT_myoblasts
- GSM7792155 WT_diffMyotubes_1 WT_diffMyotubes
- GSM7792156 WT_diffMyotubes_2 WT_diffMyotubes
- GSM7792157 WT_diffMyotubes_3 WT_diffMyotubes
- GSM7792158 WT_fusedMyotubes_1 WT_fusedMyotubes
- GSM7792159 WT_fusedMyotubes_2 WT_fusedMyotubes
- GSM7792160 WT_fusedMyotubes_3 WT_fusedMyotubes
- GSM7792161 WT_fusedMyotubes_4 WT_fusedMyotubes
- GSM7792162 Glud1KO_myoblasts_1 Glud1KO_myoblasts
- GSM7792163 Glud1KO_myoblasts_2 Glud1KO_myoblasts
- GSM7792164 Glud1KO_myoblasts_3 Glud1KO_myoblasts
- GSM7792165 Glud1KO_diffMyotubes_1 Glud1KO_diffMyotubes
- GSM7792166 Glud1KO_diffMyotubes_2 Glud1KO_diffMyotubes
- GSM7792167 Glud1KO_fusedMyotubes_1 Glud1KO_fusedMyotubes
- GSM7792168 Glud1KO_fusedMyotubes_2 Glud1KO_fusedMyotubes
- GSM7792169 Glud1KO_fusedMyotubes_3 Glud1KO_fusedMyotubes
- GSM7792170 Glud1KO_fusedMyotubes_4 Glud1KO_fusedMyotubes
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- GSE316731 Endothelial Cell-specific Activation of NOX1 Drives Obesity and Metabolic Syndrome via Skeletal Muscle Mitochondrial Dysfunction with Novel Genetic Signatures 12 samples shares mitochondrial, muscle
- GSE255246 Intrauterine hyperglycemia during late gestation caused mitochondrial dysfunction in skeletal muscle of male offspring through CREB/PGC1A signaling 10 samples shares mitochondrial, muscle
- GSE261595 The spatiotemporal expression profile of ATF3 determines the fate of smooth muscle cells in abdominal aortic aneurysm development 10 samples shares determines, muscle
- GSE284208 The Dlk1-Dio3 noncoding RNA cluster coordinately regulates mitochondrial respiration and chromatin structure to establish proper cell state for muscle differentiation [ATAC-Seq] 16 samples shares mitochondrial, muscle
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.