Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity [RNA-seq: cultured cells]
RNA-seq (gene expression) · mouse · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 4 × WT TH2 7d vs 4 × Ago134 TH2 7d vs 3 × WT TH2 14d vs 3 × Ago134 TH2 14dGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243700_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1019659 and SRA study SRP462472. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 4 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7794475 WT TH2 7d 001 WT TH2 7d
- GSM7794476 WT TH2 7d 002 WT TH2 7d
- GSM7794477 WT TH2 7d 003 WT TH2 7d
- GSM7794478 WT TH2 7d 004 WT TH2 7d
- GSM7794479 Ago134 TH2 7d 001 Ago134 TH2 7d
- GSM7794480 Ago134 TH2 7d 002 Ago134 TH2 7d
- GSM7794481 Ago134 TH2 7d 003 Ago134 TH2 7d
- GSM7794482 Ago134 TH2 7d 004 Ago134 TH2 7d
- GSM7794483 WT TH2 14d 001 WT TH2 14d
- GSM7794484 WT TH2 14d 002 WT TH2 14d
- GSM7794485 WT TH2 14d 003 WT TH2 14d
- GSM7794486 Ago134 TH2 14d 001 Ago134 TH2 14d
- GSM7794487 Ago134 TH2 14d 002 Ago134 TH2 14d
- GSM7794488 Ago134 TH2 14d 003 Ago134 TH2 14d
- GSE244066 Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity [RNA-seq: dissected tissues] 78 samples shares type-2, argonaute3-sf3b3, controls, pre-mrna, splicing, restrain, immunity
- GSE243918 Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain Type-2 immunity 128 samples shares type-2, argonaute3-sf3b3, controls, pre-mrna, splicing, restrain, immunity
- GSE242147 CRISPR-Cas screen in ILC2 identifies Mef2d as a regulator of GATA3 and type-2 immunity 36 samples shares type-2, immunity
- GSE242030 CRISPR-Cas screen in ILC2 identifies Mef2d as a regulator of GATA3 and type-2 immunity [ChIP-Seq] 17 samples shares type-2, immunity
- GSE27218 Disrupted processing of long pre-mRNAs and widespread RNA missplicing are components of neuronal vulnerability from loss of nuclear TDP-43 (RNA-seq) 21 samples shares pre-mrna, splicing
- GSE308755 A neuroepithelial rheostat controls enteric type 1 and type 2 immunity [scRNA-seq] 12 samples shares controls, immunity
- GSE229198 Tonic type 2 immunity controls autoimmunity in the skin 12 samples shares controls, immunity
- GSE205438 RNA splicing controls organ-wide maturation of postnatal heart in mice 88 samples shares controls, splicing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.