GEO series
An Optimized Hepatocyte-like Cells Differentiation Protocol Using Machine Learning Assisted Approach and Multi-omics Analysis [RNA-seq and ATAC-seq]
GSE243881
Homo sapiens
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
26 samples
2025/12/31
GPL20795
Summary
The hepatocyte is a vital cell type responsible for numerous physiological processes in the body. We developed a machine learning-based AI algorithm to monitor morphological changes in hESCs during their differentiation into mature hepatocytes.Furthermore, we developed a modified strategy that safely and efficiently produces HLCs from hESCs.
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