Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing
DNA methylation · mouse · 127 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 127 samples: 126 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Temporal and regional X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencingNature structural & molecular biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243943_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1020766 and SRA study SRP462990. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 127 sample titles: 126 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7798640 Epiblast female WT 1
- GSM7798643 Epiblast female WT 2
- GSM7798647 E9.5_1,PGC,XX
- GSM7798648 E9.5_10,Soma,XX
- GSM7798649 E9.5_11,Soma,XX
- GSM7798650 E9.5_12,Soma,XX
- GSM7798651 E9.5_13,PGC,XX
- GSM7798652 E9.5_15,PGC,XX
- GSM7798653 E9.5_16,PGC,XY
- GSM7798654 E9.5_18,PGC,XX
- GSM7798655 E9.5_19,PGC,XX
- GSM7798656 E9.5_2,PGC,XX
- GSM7798657 E9.5_20,PGC,XY
- GSM7798658 E9.5_22,PGC,XY
- GSM7798659 E9.5_23,PGC,XX
- GSM7798660 E9.5_24,PGC,XX
- GSM7798661 E9.5_25,PGC,XX
- GSM7798662 E9.5_26,PGC,XX
- GSM7798663 E9.5_27,PGC,XX
- GSM7798664 E9.5_28,PGC,XY
- GSM7798665 E9.5_3,PGC,XX
- GSM7798666 E9.5_4,PGC,XX
- GSM7798667 E9.5_41,PGC,XY
- GSM7798668 E9.5_43,PGC,XY
- GSM7798669 E9.5_44,PGC,XX
- GSM7798670 E9.5_45,PGC,XY
- GSM7798671 E9.5_46,Soma,XX
- GSM7798672 E9.5_5,PGC,XX
- GSM7798673 E9.5_6,PGC,XX
- GSM7798674 E9.5_7,PGC,XX
- GSM7798675 E9.5_8,PGC,XX
- GSM7798676 E9.5_9,Soma,XX
- GSM7798677 E10.5_14,PGC,XX
- GSM7798678 E10.5_19,PGC,XX
- GSM7798679 E10.5_2,PGC,XX
- GSM7798680 E10.5_20,PGC,XY
- GSM7798681 E10.5_21,PGC,XY
- GSM7798682 E10.5_22,PGC,XY
- GSM7798683 E10.5_23,PGC,XX
- GSM7798684 E10.5_24,PGC,XX
+ 87 more — browse all 127 samples with per-sample file links →
- GSE243942 Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing [RNA-seq] 125 samples shares spatio-temporal, site-specific, reactivation, epigenetic, retention, silencing, x-linked, germline
- GSE301448 Epigenetic Reactivation of CNS Endothelial Developmental Programs Triggers Adult Brain Angiogenesis, Promotes Post-Stroke Revascularization and Neuroregeneration [RNAseq-Stroke] 18 samples shares reactivation, epigenetic
- GSE255987 Brain-wide AAV-mediated silencing of prion protein by a compact epigenetic editor 15 samples shares epigenetic, silencing
- GSE309415 Bile acid receptor Tgr5 prevents macrophage hyperinflammation during bacterial sepsis through metabolic and epigenetic silencing 12 samples shares epigenetic, silencing
- GSE241770 ACSS2 mediates an epigenetic pathway to regulate maternal Beta-cell adaptation and progression of gestational diabetes (scRNA-Seq) 7899 samples shares epigenetic
- GSE280168 The spatial zonation of the placental vasculature is specified by epigenetic mechanisms 383 samples shares epigenetic
- GSE166225 Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates [RNA-seq] 288 samples shares spatio-temporal
- GSE276632 Reciprocal genetic screens identify epigenetics factors controlling epidermal cell activation. 262 samples shares epigenetic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.