The mitotic STAG3–cohesin complex shapes male germline nucleome [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 92 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 92 samples: 44 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The mitotic STAG3-cohesin complex shapes male germline nucleomeNature structural & molecular biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243959_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1020805 and SRA study SRP463013. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 92 samples.
How we read this: 44 replicated groups read from 92 sample titles; they account for 92 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7799815 ESC_Stag3OEStag1Stag2dKO_GFP_1 ESC_Stag3OEStag1Stag2dK…
- GSM7799816 ESC_Stag3OEStag1Stag2dKO_Rad21_1 ESC_Stag3OEStag1Stag2dK…
- GSM7799817 ESC_Stag3OEStag1Stag2dKO_Rad21_2 ESC_Stag3OEStag1Stag2dK…
- GSM7799818 ESC_Stag3OEStag1Stag2dKO_Stag3_1 ESC_Stag3OEStag1Stag2dK…
- GSM7799819 ESC_Stag3OEStag1Stag2dKO_Stag3_2 ESC_Stag3OEStag1Stag2dK…
- GSM7799820 ESC_WT_Stag1_1 ESC_WT_Stag1
- GSM7799821 ESC_WT_Stag1_2 ESC_WT_Stag1
- GSM7799822 ESC_WT_Stag2_1 ESC_WT_Stag2
- GSM7799823 ESC_WT_Stag2_2 ESC_WT_Stag2
- GSM7799824 EpiLC_WT_Stag1_1 EpiLC_WT_Stag1
- GSM7799825 EpiLC_WT_Stag1_2 EpiLC_WT_Stag1
- GSM7799826 EpiLC_WT_Stag2_1 EpiLC_WT_Stag2
- GSM7799827 EpiLC_WT_Stag2_2 EpiLC_WT_Stag2
- GSM7799828 GSC_Stag1Stag2dKO_CTCF_1 GSC_Stag1Stag2dKO_CTCF
- GSM7799829 GSC_Stag1Stag2dKO_Input_1 GSC_Stag1Stag2dKO_Input
- GSM7799830 GSC_Stag1Stag2dKO_K9me3_1 GSC_Stag1Stag2dKO_K9me3
- GSM7799831 GSC_Stag1Stag2dKO_Rad21_1 GSC_Stag1Stag2dKO_Rad21
- GSM7799832 GSC_Stag1Stag2dKO_Rad21_2 GSC_Stag1Stag2dKO_Rad21
- GSM7799833 GSC_Stag1Stag2dKO_Stag3_1 GSC_Stag1Stag2dKO_Stag3
- GSM7799834 GSC_Stag1Stag2dKO_Stag3_2 GSC_Stag1Stag2dKO_Stag3
- GSM7799835 GSC_Stag1Stag3dKO_CTCF_1 GSC_Stag1Stag3dKO_CTCF
- GSM7799836 GSC_Stag1Stag3dKO_Input_1 GSC_Stag1Stag3dKO_Input
- GSM7799837 GSC_Stag1Stag3dKO_Rad21_1 GSC_Stag1Stag3dKO_Rad21
- GSM7799838 GSC_Stag1Stag3dKO_Rad21_2 GSC_Stag1Stag3dKO_Rad21
- GSM7799839 GSC_Stag1Stag3dKO_Stag2_1 GSC_Stag1Stag3dKO_Stag2
- GSM7799840 GSC_Stag1Stag3dKO_Stag2_2 GSC_Stag1Stag3dKO_Stag2
- GSM7799841 GSC_Stag2Stag3dKO_CTCF_1 GSC_Stag2Stag3dKO_CTCF
- GSM7799842 GSC_Stag2Stag3dKO_Input_1 GSC_Stag2Stag3dKO_Input
- GSM7799843 GSC_Stag2Stag3dKO_K9me3_1 GSC_Stag2Stag3dKO_K9me3
- GSM7799844 GSC_Stag2Stag3dKO_Rad21_1 GSC_Stag2Stag3dKO_Rad21
- GSM7799845 GSC_Stag2Stag3dKO_Rad21_2 GSC_Stag2Stag3dKO_Rad21
- GSM7799846 GSC_Stag2Stag3dKO_Stag1_1 GSC_Stag2Stag3dKO_Stag1
- GSM7799847 GSC_Stag2Stag3dKO_Stag1_2 GSC_Stag2Stag3dKO_Stag1
- GSM7799848 GSC_Stag3KO_CTCF_1 GSC_Stag3KO_CTCF
- GSM7799849 GSC_Stag3KO_Input_1 GSC_Stag3KO_Input
- GSM7799850 GSC_Stag3KO_K27ac_1 GSC_Stag3KO_K27ac
- GSM7799851 GSC_Stag3KO_K27me3_1 GSC_Stag3KO_K27me3
- GSM7799852 GSC_Stag3KO_Rad21_1 GSC_Stag3KO_Rad21
- GSM7799853 GSC_Stag3KO_Stag3_1 GSC_Stag3KO_Stag3
- GSM7799854 GSC_Stag3KO_Stag3_2 GSC_Stag3KO_Stag3
+ 52 more — browse all 92 samples with per-sample file links →
- GSE268146 Integrator complex bridges TFIID and RNA polymerase II to maintain pluripotency during development (ChIP-Seq) 38 samples shares chip-seq, complex
- GSE163008 Loop extrusion by cohesin plays a role in enhancer-activated gene expression early in differentiation (ChIP-seq) 26 samples shares chip-seq, cohesin
- GSE270581 Chromatin distribution alterations of histone modifacations and PRC2 complex caused by Rack7 deletion in primary astrocyte [ChIP-Seq] 24 samples shares chip-seq, complex
- GSE318256 TET1 non-catalytic activity shapes the chromatin-landscape that directs de novo methylation establishment in the male germline 44 samples shares germline, shapes
- GSE261221 Scaffolding element rewires genome architecture during differentiation at the Zfp608 locus (ChIP-Seq) 189 samples shares chip-seq
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares chip-seq
- GSE303384 Mechanism of maintenance and establishment of repression by the Mtg16 tumor suppressor [CUT&RUN, ChIP-Seq] 92 samples shares chip-seq
- GSE309572 MLL2 facilitates long-range gene regulation through LINE1 elements [ChIP-Seq] 89 samples shares chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.