All-defined NGN2 neuron protocol reveals multifaceted signatures of neuronal maturation [bulk timecourse]
RNA-seq (gene expression) · human · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 15 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturationCell reports methods · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244369_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1022482 and SRA study SRP463940. Searching any of these in the dataset finder brings you back here.
The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Sample titles run SAM24425282 … SAM24425296 and carry no group information.
- GSM7814294 SAM24425282
- GSM7814295 SAM24425283
- GSM7814296 SAM24425284
- GSM7814297 SAM24425285
- GSM7814298 SAM24425286
- GSM7814299 SAM24425287
- GSM7814300 SAM24425288
- GSM7814301 SAM24425289
- GSM7814302 SAM24425290
- GSM7814303 SAM24425291
- GSM7814304 SAM24425292
- GSM7814305 SAM24425293
- GSM7814306 SAM24425294
- GSM7814307 SAM24425295
- GSM7814308 SAM24425296
- GSE244368 All-defined NGN2 neuron protocol reveals multifaceted signatures of neuronal maturation [bulk_media] 10 samples shares ngn2, multifaceted, all-defined, signatures, maturation, protocol, neuronal
- GSE279593 BMP, MEK and WNT modulation with NGN2 expression for rapid neuron differentiation from hiPSC amenable to regional patterning 158 samples shares ngn2
- GSE279590 BMP, MEK and WNT modulation with NGN2 expression for rapid generation of hiPSC-derived neurons amenable to regional patterning [bulk RNA-seq] 61 samples shares ngn2
- GSE112650 SOX4/11 Enhances NGN2 Reprogramming Glioblastoma Cells into Neuron Cells by Modulating RhoA and CDC42/RAC1 Pathway Activity 30 samples shares ngn2
- GSE286042 Transcriptomic and Proteomic Signatures Following AS03-adjuvanted Influenza A/H7N9 Vaccine 1232 samples shares signatures
- GSE86469 Single cell transcriptomics defines human islet cell signatures and reveals cell-type-specific expression changes in type 2 diabetes [single cell] 638 samples shares signatures
- GSE270568 Polyploid cancer cells reveal signatures of chemotherapy relapse [scRNA-seq] 605 samples shares signatures
- GSE287043 Unique Mycobacterium tuberculosis-specific blood immune signatures in sarcoidosis: implications for clinical diagnosis 542 samples shares signatures
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.