GEO series
Polyploid cancer cells reveal signatures of chemotherapy relapse [scRNA-seq]
GSE270568
Homo sapiens
Expression profiling by high throughput sequencing
605 samples
2024/09/13
GPL20301
Summary
Treatment of PC3 and MDA-MB-231 cell lines with sublethal doses of docetaxel or cisplatin in vitro resulted in induction of polyploid cancer cells. Single cell copy RNA-sequencing was conducted to understand resistance of polyploid cancer cells to chemotherapy.
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Paper (PMID 39229204) ↗
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