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Multi-organ single-cell RNA-sequencing of early hyperglycaemia responses

GSE244475 Mus musculus Expression profiling by high throughput sequencing 7 samples Submitted 2024/10/18 Platform GPL24247
Summary
Diabetes causes a range of complications that can affect multiple organs. Hyperglycaemia is an important driver of diabetes-associated complications, mediated by biological processes such as dysfunction of endothelial cells, fibrosis and alterations in leukocyte number and function. Here, we dissected the transcriptional response of key cell types to hyperglycaemia across multiple tissues using single-cell RNA-seq.
Published in
Multi-organ single-cell RNA sequencing in mice reveals early hyperglycemia responses that converge on fibroblast dysregulation
Braithwaite AT, Akbar N, Pezzolla D et al. · FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 · PMID 38305779 · doi:10.1096/fj.202302003R
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Direct links to NCBI, no account and no request form: the whole study as GSE244475_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 7 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1023243 and SRA study SRP464259. Searching any of these in the dataset finder brings you back here.

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