Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restrictionThe EMBO journal · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244709_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1024426 and SRA study SRP464828. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 9 samples read as cases, 11 as controls.
How we read this: 9 replicated groups read from 20 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7824623 control scRNAseq
- GSM7824624 mutant scRNAseq
- GSM7824625 control ATACseq rep1 control ATACseq
- GSM7824626 control ATACseq rep2 control ATACseq
- GSM7824627 mutant ATACseq rep1 mutant ATACseq
- GSM7824628 mutant ATACseq rep2 mutant ATACseq
- GSM7824629 control CUT&TAG H3K4me1 rep1 control CUT&TAG H3K4me1
- GSM7824630 control CUT&TAG H3K4me1 rep2 control CUT&TAG H3K4me1
- GSM7824631 mutant CUT&TAG H3K4me1 rep1 mutant CUT&TAG H3K4me1
- GSM7824632 mutant CUT&TAG H3K4me1 rep2 mutant CUT&TAG H3K4me1
- GSM7824633 control CUT&TAG H3K27ac rep1 control CUT&TAG H3K27ac
- GSM7824634 control CUT&TAG H3K27ac rep2 control CUT&TAG H3K27ac
- GSM7824635 mutant CUT&TAG H3K27ac rep1 mutant CUT&TAG H3K27ac
- GSM7824636 mutant CUT&TAG H3K27ac rep2 mutant CUT&TAG H3K27ac
- GSM7824637 control CUT&TAG H3K27me3 rep1 control CUT&TAG H3K27m…
- GSM7824638 control CUT&TAG H3K27me3 rep2 control CUT&TAG H3K27m…
- GSM7824639 mutant CUT&TAG H3K27me3 rep1 mutant CUT&TAG H3K27me3
- GSM7824640 mutant CUT&TAG H3K27me3 rep2 mutant CUT&TAG H3K27me3
- GSM7824641 control CUT&TAG Tcf4-tag rep1 control CUT&TAG Tcf4-tag
- GSM7824642 control CUT&TAG Tcf4-tag rep2 control CUT&TAG Tcf4-tag
- GSE11291 Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle 60 samples shares restriction, brain
- GSE248866 The outcomes of caloric restriction are driven by enhanced glucocorticoid rhythms. 114 samples shares restriction
- GSE298149 The outcomes of caloric restriction are driven by enhanced glucocorticoid rhythms. 16 samples shares restriction
- GSE290581 Restriction of innate Tgd17 cell plasticity by an AP-1 regulatory axis 13 samples shares restriction
- GSE276572 Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity. 12 samples shares restriction
- GSE294530 Mosaic gastruloids reveal a temporal restriction for developmental cell competition 69 samples shares restriction
- GSE278025 Maternal Micronutrient Insufficiency Exacerbates Growth Restriction with Ambient Heat on Placental and Fetal Development during Pregnancy 24 samples shares restriction
- GSE169555 Embryonic lumenogenesis is controlled by selective mRNA decay triggered by LIN28A relocation 146 samples shares controlled
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.