Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy.
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 54 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 54 samples: 18 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathyNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244812_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1024933 and SRA study SRP464893. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 42 samples.
How we read this: 18 replicated groups read from 54 sample titles; they account for 42 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7830180 Normal_K27ac Normal_K27ac
- GSM7830181 Normal_K27me3
- GSM7830182 Normal_K4me1 Normal_K4me
- GSM7830183 Normal_K4me3 Normal_K4me
- GSM7830184 Normal_K36me3
- GSM7830185 Normal_K9me3
- GSM7830186 PVR_K27ac PVR_K27ac
- GSM7830187 PVR_K27me3
- GSM7830188 PVR_K4me1 PVR_K4me
- GSM7830189 PVR_K4me3 PVR_K4me
- GSM7830190 PVR_K36me3
- GSM7830191 PVR_K9me3
- GSM7830192 Normal_ATAC Normal_ATAC
- GSM7830193 PVR_ATAC PVR_ATAC
- GSM7830194 Normal_1_RNA
- GSM7830195 PVR_1_RNA
- GSM7830196 Normal_2_RNA
- GSM7830197 PVR_2_RNA
- GSM8174689 Normal_K27ac_2 Normal_K27ac
- GSM8174690 Normal_K27me3_2 Normal_K27me3
- GSM8174691 Normal_K4me1_2 Normal_K4me1
- GSM8174692 Normal_K4me3_2 Normal_K4me3
- GSM8174693 Normal_K36me3_2 Normal_K36me3
- GSM8174694 Normal_K9me3_2 Normal_K9me3
- GSM8174695 Normal_K27ac_3 Normal_K27ac
- GSM8174696 Normal_K27me3_3 Normal_K27me3
- GSM8174697 Normal_K4me1_3 Normal_K4me1
- GSM8174698 Normal_K4me3_3 Normal_K4me3
- GSM8174699 Normal_K36me3_3 Normal_K36me3
- GSM8174700 Normal_K9me3_3 Normal_K9me3
- GSM8174701 PVR_K27ac_2 PVR_K27ac
- GSM8174702 PVR_K27me3_2 PVR_K27me3
- GSM8174703 PVR_K4me1_2 PVR_K4me1
- GSM8174704 PVR_K4me3_2 PVR_K4me3
- GSM8174705 PVR_K36me3_2 PVR_K36me3
- GSM8174706 PVR_K9me3_2 PVR_K9me3
- GSM8174707 PVR_K27ac_3 PVR_K27ac
- GSM8174708 PVR_K27me3_3 PVR_K27me3
- GSM8174709 PVR_K4me1_3 PVR_K4me1
- GSM8174710 PVR_K4me3_3 PVR_K4me3
+ 14 more — browse all 54 samples with per-sample file links →
- GSE244809 Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy [ChIP-seq] 42 samples shares vitreoretinopathy, enhancer-driven, proliferative, multi-omics, rank-nfatc1, epithelium, activation, traumatic
- GSE244811 Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy [RNA-seq] 6 samples shares vitreoretinopathy, enhancer-driven, proliferative, multi-omics, rank-nfatc1, epithelium, activation, traumatic
- GSE244810 Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy [ATAC-seq] 6 samples shares vitreoretinopathy, enhancer-driven, proliferative, multi-omics, rank-nfatc1, epithelium, activation, traumatic
- GSE268544 ATAC-seq of Keratinocytes and Langerhans cells in normal and hyperproliferative epithelium 16 samples shares proliferative, epithelium
- GSE296841 Multi-omics Profiling of the Lateral Ventricle Choroid Plexus Reveals Temporal Cellular Remodeling, Early Immune Gene Activation, and a Novel Epithelial Subtype [snMultiome] 12 samples shares multi-omics, activation
- GSE285349 Single-cell multi-omics analysis of the early wound-responsive programs in mouse corneal epithelium 6 samples shares multi-omics, epithelium
- GSE342312 T-bet and Runx3 orchestrate effector CD8 T cell differentiation and lineage fidelity through cooperative and distinct chromatin regulatory mechanisms [Multi-omics] 40 samples shares multi-omics
- GSE267584 Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment. 22 samples shares enhancer-driven
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.