CPSF6-RARγ Interacts with HDAC3 to Promote Myeloid Transformation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 57 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 57 samples: 17 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- CPSF6-RARγ interacts with histone deacetylase 3 to promote myeloid transformation in RARG-fusion acute myeloid leukemiaNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE245030_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1026639 and SRA study SRP523244. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 37 samples.
How we read this: 17 replicated groups read from 57 sample titles; they account for 37 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7796064 CD34+ cells, CRL expression, replicate 1 CD34+ cells, CRL expres…
- GSM7796065 CD34+ cells, CRL expression, replicate 2 CD34+ cells, CRL expres…
- GSM7796066 CD34+ cells, CRL expression, replicate 3 CD34+ cells, CRL expres…
- GSM7796067 CD34+ cells, CRS expression, replicate 1 CD34+ cells, CRS expres…
- GSM7796068 CD34+ cells, CRS expression, replicate 2 CD34+ cells, CRS expres…
- GSM7796069 CD34+ cells, CRS expression, replicate 3 CD34+ cells, CRS expres…
- GSM7796070 CD34+ cells, empty vector, replicate 1 CD34+ cells, empty vect…
- GSM7796071 CD34+ cells, empty vector, replicate 2 CD34+ cells, empty vect…
- GSM7796072 CD34+ cells, empty vector, replicate 3 CD34+ cells, empty vect…
- GSM7834674 CD34-CRL, flag antibody, CUT&Tag, replicate 1 CD34-CRL, flag antibody…
- GSM7834675 CD34-CRL, flag antibody, CUT&Tag, replicate 2 CD34-CRL, flag antibody…
- GSM7834676 CD34-CRL, IgG, CUT&Tag, replicate 1 CD34-CRL, IgG, CUT&Tag,
- GSM7834677 CD34-CRL, IgG, CUT&Tag, replicate 2 CD34-CRL, IgG, CUT&Tag,
- GSM7834678 CD34-CRS flag antibody, CUT&Tag, replicate 1
- GSM7834679 CD34-CRS, flag antibody, CUT&Tag, replicate 2
- GSM7834680 CD34-CRS, IgG, CUT&Tag, replicate 1 CD34-CRS, IgG, CUT&Tag,
- GSM7834681 CD34-CRS, IgG, CUT&Tag, replicate 2 CD34-CRS, IgG, CUT&Tag,
- GSM7834682 CD34-RARG, flag antibody, CUT&Tag, replicate 1 CD34-RARG, flag antibod…
- GSM7834683 CD34-RARG, flag antibody, CUT&Tag, replicate 2 CD34-RARG, flag antibod…
- GSM7834684 CD34-RARG, IgG, CUT&Tag, replicate 1 CD34-RARG, IgG, CUT&Tag,
- GSM7834685 CD34-RARG, IgG, CUT&Tag, replicate 2 CD34-RARG, IgG, CUT&Tag,
- GSM7834984 WT, replicate 1 WT,
- GSM7834985 WT, replicate 2 WT,
- GSM7834986 LysM-CRL, replicate 1 LysM-CRL,
- GSM7834987 LysM-CRL, replicate 2 LysM-CRL,
- GSM7834988 LysM-CRS, replicate 1 LysM-CRS,
- GSM7834989 LysM-CRS, replicate 2 LysM-CRS,
- GSM7897869 WT/V, replicate 1 WT/V,
- GSM7897870 WT/V, replicate 2 WT/V,
- GSM7897871 WT/N, replicate 1 WT/N,
- GSM7897872 WT/N, replicate 2 WT/N,
- GSM7897873 CRL/V, replicate 1 CRL/V,
- GSM7897874 CRL/V, replicate 2 CRL/V,
- GSM7897875 CRL/N, replicate 1 CRL/N,
- GSM7897876 CRL/N, replicate 2 CRL/N,
- GSM7897877 CRS/V, replicate 1 CRS/V,
- GSM7897878 CRS/V, replicate 2 CRS/V,
- GSM7897879 CRS/N, replicate 1 CRS/N,
- GSM7897880 CRS/N, replicate 2 CRS/N,
- GSM8432154 CD34-CRL, H3K27me3 antibody, CUT&Tag
+ 17 more — browse all 57 samples with per-sample file links →
- GSE45982 EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation 61 samples shares transformation, promote
- GSE20281 The transcriptional network for mesenchymal transformation of brain tumours 108 samples shares transformation
- GSE261742 Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens 69 samples shares transformation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.