GEO series
AT2-specific knockout of SLC39A1 in murine model of acute lung injury
GSE245055
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2026/02/11
GPL24247
Summary
Acute lung injury (ALI) is a common severe respiratory syndrome, with nearly 3 million new ARDS patients worldwide every year. There is no clear effective treatment for ALI.The zinc ion transporters that mediate the change of zinc ion content in target cells during pathophysiology are very different and exert very different biological effects.We identified key zinc ion transporters in ALI and found that SLC39A1 may play an important role in transporting zinc ions during ALI and mediate zinc uptake in AT2 cells.
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