GEO series
Oncofetal reprogramming of the tumor vasculature
GSE245218
Mus musculus
Expression profiling by high throughput sequencing
13 samples
2025/04/09
GPL13112
Summary
Certain embryonic genes, such as carcinoembryonic antigens (CEA) and oncofetal antigens, become re-expressed in malignant transformation and we hypothesized that a similar phenomenon features tumor endothelial cells as well. Therefore, we performed a systematic search for mouse embryo-specific gene expression at days E11 and E18 in comparison to adult mouse and queried for overexpression of these genes in sorted murine tumor endothelial cells.
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Paper (PMID 40096611) ↗
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