GEO series
Transcriptome Profile of IEC4.1 cells deficient with Prdm1 in response to IFN-gamma
GSE245345
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/05/30
GPL28457
Summary
This study is to investigate the potential role of Prdm1 in murine intestinal epithelial cells (IEC4.1 cells) in response to IFN gamma stimulation. Prdm1 was knocked down in IEC4.1 cells by using a CRISPR/Cas9 approach. Wild type IEC4.1 cells were used as control (Ctrl). Cells were treated with or without mouse IFN gamma (1ng/ml for 4hrs). Then total RNA was collected for sequencing via DNBSEQ platform to obtain a comprehensive view of the transcriptome.
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Paper (PMID 40497734) ↗
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