KPT-330-modulated cold adaptation in various thermogenic organs of prediabetic mice
RNA-seq (gene expression) · mouse · 68 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 68 samples: 68 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cold-induced FOXO1 nuclear transport aids cold survival and tissue storageNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE246327_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1032547 and SRA study SRP468603. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 68 sample titles: 68 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7866762 496MUS
- GSM7866763 497MUS
- GSM7866764 B679MUS
- GSM7866765 3MUS
- GSM7866766 498MUS
- GSM7866767 AB45MUS
- GSM7866768 Aa127MUS
- GSM7866769 405MUS
- GSM7866770 B652MUS
- GSM7866771 Aa121MUS
- GSM7866772 494MUS
- GSM7866773 500MUS
- GSM7866774 2MUS
- GSM7866775 T781MUS
- GSM7866776 4MUS
- GSM7866777 Ab22MUS
- GSM7866778 499MUS
- GSM7866779 496BAT
- GSM7866780 497BAT
- GSM7866781 B679BAT
- GSM7866782 3BAT
- GSM7866783 498BAT
- GSM7866784 AB45BAT
- GSM7866785 Aa127BAT
- GSM7866786 405BAT
- GSM7866787 B652BAT
- GSM7866788 Aa121BAT
- GSM7866789 494BAT
- GSM7866790 500BAT
- GSM7866791 2BAT
- GSM7866792 T781BAT
- GSM7866793 4BAT
- GSM7866794 Ab22BAT
- GSM7866795 499BAT
- GSM7866796 496WAT
- GSM7866797 497WAT
- GSM7866798 B679WAT
- GSM7866799 3WAT
- GSM7866800 498WAT
- GSM7866801 AB45WAT
+ 28 more — browse all 68 samples with per-sample file links →
- GSE241770 ACSS2 mediates an epigenetic pathway to regulate maternal Beta-cell adaptation and progression of gestational diabetes (scRNA-Seq) 7899 samples shares adaptation
- GSE215959 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma [M4_aCTLA4_scRNA] 1248 samples shares adaptation
- GSE295250 Conserved Noncoding Cis-Elements Associated with Hibernation Modulate Metabolic and Behavioral Adaptations in Mice [RNA-seq] 72 samples shares adaptation
- GSE215960 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma [scRNA-seq] 192 samples shares adaptation
- GSE218178 Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance 183 samples shares adaptation
- GSE218173 Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance [acid] 150 samples shares adaptation
- GSE248964 Isoform Usage as a Distinct Regulatory Layer Driving Nutrient-Responsive Metabolic Adaptation (RNA-seq) 117 samples shares adaptation
- GSE293286 Metabolic adaptations direct cell fate during tissue regeneration [shOGDH_Mice_RNA-seq] 12 samples shares adaptation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.