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Gene expression analysis of mouse F1 hybrids to study cis regulatory variations

GSE246401 Mus musculus Expression profiling by high throughput sequencing; Other 4 samples Submitted 2024/05/31 Platform GPL21273
Summary
To analyze the difference in gene expression between alleles of F1 hybrids of mouse C57BL6/J (B6) and MSM/Ms (MSM) strains, we sequenced these F1 hybrids of reciprocal crosses. While most genes did show allelic bias, a small number of genes showed either B6- or MSM-biaed expression in both crosses. These allelic differences were associated with the allelic differences in histone acetylation in promoter regions determined by another experiments.
Published in
Insertion of short L1 sequences generates inter-strain histone acetylation differences in the mouse
Boyboy BAG, Ichiyanagi K · Mobile DNA 2024 · PMID 38730323 · doi:10.1186/s13100-024-00321-0
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Direct links to NCBI, no account and no request form: the whole study as GSE246401_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1032874 and SRA study SRP468785. Searching any of these in the dataset finder brings you back here.

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