Regulatory T cells in the Tumor Microenvironment Display a Unique Chromatin Accessibility Profile (ATAC-Seq)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 140 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 140 samples: 51 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Regulatory T cells in the tumor microenvironment display a unique chromatin accessibility profileImmunoHorizons · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE246700_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1034147 and SRA study SRP469522. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 139 samples.
How we read this: 51 replicated groups read from 140 sample titles; they account for 139 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7874813 B16_Treg LN Day 8_1 B16_Treg LN Day 8
- GSM7874814 B16_Treg LN Day 8_2 B16_Treg LN Day 8
- GSM7874815 B16_Treg LN Day 12_1 B16_Treg LN Day 12
- GSM7874816 B16_Treg LN Day 12_2 B16_Treg LN Day 12
- GSM7874817 B16_Treg LN Day 16_1 B16_Treg LN Day 16
- GSM7874818 B16_Treg LN Day 16_2 B16_Treg LN Day 16
- GSM7874819 B16_Treg LN Day 20_1 B16_Treg LN Day 20
- GSM7874820 B16_Treg LN Day 20_2 B16_Treg LN Day 20
- GSM7874821 B16_Treg TIL Day 8_1 B16_Treg TIL Day 8
- GSM7874822 B16_Treg TIL Day 8_2 B16_Treg TIL Day 8
- GSM7874823 B16_Treg TIL Day 12_1 B16_Treg TIL Day 12
- GSM7874824 B16_Treg TIL Day 12_2 B16_Treg TIL Day 12
- GSM7874825 B16_Treg TIL Day 16_1 B16_Treg TIL Day 16
- GSM7874826 B16_Treg TIL Day 16_2 B16_Treg TIL Day 16
- GSM7874827 B16_Treg TIL Day 20_1 B16_Treg TIL Day 20
- GSM7874828 B16_Treg TIL Day 20_2 B16_Treg TIL Day 20
- GSM7874829 MC38_Treg LN Day 8_1 MC38_Treg LN Day 8
- GSM7874830 MC38_Treg LN Day 8_2 MC38_Treg LN Day 8
- GSM7874831 MC38_Treg LN Day 12_1 MC38_Treg LN Day 12
- GSM7874832 MC38_Treg LN Day 12_2 MC38_Treg LN Day 12
- GSM7874833 MC38_Treg LN Day 16_1 MC38_Treg LN Day 16
- GSM7874834 MC38_Treg LN Day 16_2 MC38_Treg LN Day 16
- GSM7874835 MC38_Treg LN Day 20_1 MC38_Treg LN Day 20
- GSM7874836 MC38_Treg LN Day 20_2 MC38_Treg LN Day 20
- GSM7874837 MC38_Treg TIL Day 8_1 MC38_Treg TIL Day 8
- GSM7874838 MC38_Treg TIL Day 8_2 MC38_Treg TIL Day 8
- GSM7874839 MC38_Treg TIL Day 12_1 MC38_Treg TIL Day 12
- GSM7874840 MC38_Treg TIL Day 12_2 MC38_Treg TIL Day 12
- GSM7874841 MC38_Treg TIL Day 16_1 MC38_Treg TIL Day 16
- GSM7874842 MC38_Treg TIL Day 16_2 MC38_Treg TIL Day 16
- GSM7874843 MC38_Treg TIL Day 20_1 MC38_Treg TIL Day 20
- GSM7874844 MC38_Treg TIL Day 20_2 MC38_Treg TIL Day 20
- GSM7874845 B16_CD4 LN Day 8_1 B16_CD4 LN Day 8
- GSM7874846 B16_CD4 LN Day 8_2 B16_CD4 LN Day 8
- GSM7874847 B16_CD4 LN Day 12_1 B16_CD4 LN Day 12
- GSM7874848 B16_CD4 LN Day 12_2 B16_CD4 LN Day 12
- GSM7874849 B16_CD4 LN Day 16_1 B16_CD4 LN Day 16
- GSM7874850 B16_CD4 LN Day 16_2 B16_CD4 LN Day 16
- GSM7874851 B16_CD4 LN Day 20_1 B16_CD4 LN Day 20
- GSM7874852 B16_CD4 LN Day 20_2 B16_CD4 LN Day 20
+ 100 more — browse all 140 samples with per-sample file links →
- GSE264229 Mapping the male mouse chromatin accessibility landscape by UUATAC-seq 33 samples shares accessibility, chromatin, atac-seq
- GSE249077 Mapping the female mouse chromatin accessibility landscape by UUATAC-seq 23 samples shares accessibility, chromatin, atac-seq
- GSE342565 Chromatin accessibility profiling of high endothelial cells (HECs) from mouse peripheral lymph node and Peyer's patch by ATAC-seq 2 samples shares accessibility, chromatin, atac-seq
- GSE216371 A single-cell atlas of chromatin accessibility in mouse organogenesis 68 samples shares accessibility, chromatin
- GSE294103 SIRT6 Overexpression Counteracts Chromatin Aging [ATAC-Seq_tg] 28 samples shares chromatin, atac-seq
- GSE246986 Ki67-mediated chromatin accessibility impedes B-cell antigen-receptor gene rearrangement 24 samples shares accessibility, chromatin
- GSE233039 The H3K9me3 heterochromatin integrity and function are sustained by H3K9me3 methyltransferases-HP1 dependencies [ATAC-Seq] 18 samples shares chromatin, atac-seq
- GSE283483 Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression programs in the hippocampus 160 samples shares accessibility, chromatin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.