GEO series
Comprehensive bioinformatics analysis reveals the hub genes and pathways in a mouse model of Pierpont Syndrome
GSE246719
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/10/31
GPL24247
Summary
Unravelling molecular defects resulting from the missense mutation in TBL1XR1 using targeted mutant mice bearing the Tbl1xr1 Y446C/Y446C mutation. These mice used as an animal model of Pierpont syndrome have disturbed hearing and a trend for disturbed locomotor activity. RNA seq of cortex tissue has been performed to establish the transcriptome.
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Paper (PMID 38885822) ↗
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