H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 149 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 149 samples: 74 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- H3K36 methylation regulates cell plasticity and regeneration in the intestinal epitheliumNature cell biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE247253_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1036690 and SRA study SRP470625. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 148 samples.
How we read this: 74 replicated groups read from 149 sample titles; they account for 148 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7885890 IR24, H3K27me3, regen, rep1 IR24, H3K27me3, regen,
- GSM7885891 IR24, H3K36me2, regen, rep1 IR24, H3K36me2, regen,
- GSM7885892 IR24, H3K36me3, regen, rep1 IR24, H3K36me3, regen,
- GSM7885893 IR24, H3K27me3, regen, rep2 IR24, H3K27me3, regen,
- GSM7885894 IR24, H3K36me2, regen, rep2 IR24, H3K36me2, regen,
- GSM7885895 IR24, H3K36me3, regen, rep2 IR24, H3K36me3, regen,
- GSM7885896 IR48, H3K27me3, regen, rep1 IR48, H3K27me3, regen,
- GSM7885897 IR48, H3K36me2, regen, rep1 IR48, H3K36me2, regen,
- GSM7885898 IR48, H3K36me3, regen, rep1 IR48, H3K36me3, regen,
- GSM7885899 IR48, H3K27me3, regen, rep2 IR48, H3K27me3, regen,
- GSM7885900 IR48, H3K36me2, regen, rep2 IR48, H3K36me2, regen,
- GSM7885901 IR48, H3K36me3, regen, rep2 IR48, H3K36me3, regen,
- GSM7885902 IR96, H3K27me3, regen, rep1 IR96, H3K27me3, regen,
- GSM7885903 IR96, H3K36me2, regen, rep1 IR96, H3K36me2, regen,
- GSM7885904 IR96, H3K36me3, regen, rep1 IR96, H3K36me3, regen,
- GSM7885905 IR96, H3K27me3, regen, rep2 IR96, H3K27me3, regen,
- GSM7885906 IR96, H3K36me2, regen, rep2 IR96, H3K36me2, regen,
- GSM7885907 IR96, H3K36me3, regen, rep2 IR96, H3K36me3, regen,
- GSM7885908 H3K36M, H3K27me3, regen, rep1 H3K36M, H3K27me3, regen,
- GSM7885909 H3K36M, H3K36me2, regen, rep1 H3K36M, H3K36me2, regen,
- GSM7885910 H3K36M, H3K36me3, regen, rep1 H3K36M, H3K36me3, regen,
- GSM7885911 H3K36M, H3K27me3, regen, rep2 H3K36M, H3K27me3, regen,
- GSM7885912 H3K36M, H3K36me2, regen, rep2 H3K36M, H3K36me2, regen,
- GSM7885913 H3K36M, H3K36me3, regen, rep2 H3K36M, H3K36me3, regen,
- GSM7885932 WTnoIR, H3K27me3, regen, rep1 WTnoIR, H3K27me3, regen,
- GSM7885933 WTnoIR, H3K36me2, regen, rep1 WTnoIR, H3K36me2, regen,
- GSM7885934 WTnoIR, H3K36me3, regen, rep1 WTnoIR, H3K36me3, regen,
- GSM7885935 WTnoIR, H3K27me3, regen, rep2 WTnoIR, H3K27me3, regen,
- GSM7885936 WTnoIR, H3K36me2, regen, rep2 WTnoIR, H3K36me2, regen,
- GSM7885937 WTnoIR, H3K36me3, regen, rep2 WTnoIR, H3K36me3, regen,
- GSM7885938 IR24,rep1 IR24,
- GSM7885939 IR24,rep2 IR24,
- GSM7885940 IR48,rep1 IR48,
- GSM7885941 IR48,rep2 IR48,
- GSM7885942 IR96,rep1 IR96,
- GSM7885943 IR96,rep2 IR96,
- GSM7885944 K36M,rep1 K36M,
- GSM7885945 K36M,rep2 K36M,
- GSM7885952 WTnoIR,rep1 WTnoIR,
- GSM7885953 WTnoIR,rep2 WTnoIR,
+ 109 more — browse all 149 samples with per-sample file links →
- GSE275296 H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium [cutandtag_enzyme_profiling] 12 samples shares h3k36, regeneration, methylation, plasticity, intestinal, epithelium
- GSE292289 H3K79 methylation and H3K36 trimethylation synergistically regulate gene expression in pluripotent stem cells 94 samples shares h3k36, methylation
- GSE297315 Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury 41 samples shares regeneration, intestinal
- GSE338640 Vascular function underlies enhanced intestinal regeneration after FLASH radiation 26 samples shares regeneration, intestinal
- GSE337790 Vascular function underlies enhanced intestinal regeneration after FLASH radiation [bulk RNAseq] 18 samples shares regeneration, intestinal
- GSE229903 CUT&Tag analysis of H3K4me3, H3K27Ac,H2A119Ub, H3K27me3 and H3K36me3 in KPC1199 murine PDAC cell line 10 samples shares h3k36
- GSE285237 R-loop maintains the deposition of H3K36me3 to prevent invasion of H3K4me3 during SN-oocyte development [3] 15 samples shares h3k36
- GSE207943 Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas 59 samples shares plasticity
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.