Vascular function underlies enhanced intestinal regeneration after FLASH radiation
RNA-seq (gene expression) · mouse · 26 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE338640_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1495288 and SRA study SRP715741. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 26 samples.
How we read this: 6 replicated groups read from 26 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9860527 SICtrol1 SICtrol
- GSM9860528 SICtrol2 SICtrol
- GSM9860529 SICtrol3 SICtrol
- GSM9860530 SICtrol4 SICtrol
- GSM9860531 SICtrol5 SICtrol
- GSM9860532 SICtrol6 SICtrol
- GSM9860533 SIC2 SIC
- GSM9860534 SIC3 SIC
- GSM9860535 SIC5 SIC
- GSM9860536 SIC6 SIC
- GSM9860537 SIC7 SIC
- GSM9860538 SIF1 SIF
- GSM9860539 SIF2 SIF
- GSM9860540 SIF4 SIF
- GSM9860541 SIF5 SIF
- GSM9860542 SIF6 SIF
- GSM9860543 SIF7 SIF
- GSM9860544 SIF9 SIF
- GSM9878786 Ctrol_01 Ctrol
- GSM9878787 Ctrol_02 Ctrol
- GSM9878788 Ctrol_03 Ctrol
- GSM9878789 CONV_01 CONV
- GSM9878790 CONV_03 CONV
- GSM9878791 FLASH_01 FLASH
- GSM9878792 FLASH_02 FLASH
- GSM9878793 FLASH_03 FLASH
- GSE337790 Vascular function underlies enhanced intestinal regeneration after FLASH radiation [bulk RNAseq] 18 samples shares flash, regeneration, intestinal, underlies, radiation, vascular, enhanced
- GSE338639 Vascular function underlies enhanced intestinal regeneration after FLASH radiation [scRNAseq] 8 samples shares flash, regeneration, intestinal, underlies, radiation, vascular, enhanced
- GSE261367 FLASH proton radiotherapy mitigates inflammatory and fibrotic pathways and preserves cardiac function in a preclinical mouse model of radiation-induced heart disease 11 samples shares flash, radiation
- GSE301448 Epigenetic Reactivation of CNS Endothelial Developmental Programs Triggers Adult Brain Angiogenesis, Promotes Post-Stroke Revascularization and Neuroregeneration [RNAseq-Stroke] 18 samples shares regeneration, vascular
- GSE331524 Transcriptomic analysis of hippocampus and prefrontal cortex in a mouse model of chronic radiation-induced gastrointestinal injury 12 samples shares intestinal, radiation
- GSE297315 Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury 41 samples shares regeneration, intestinal
- GSE275296 H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium [cutandtag_enzyme_profiling] 12 samples shares regeneration, intestinal
- GSE307570 Localized FLASH Radiotherapy Reduces Long-Term Skin and Muscle Damage While Preserving Systemic Homeostasis 20 samples shares flash
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.