α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells [scRNA-Seq 2D]
Single-cell RNA-seq · human · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cellsNature cell biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE247633_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1039846 and SRA study SRP471567. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE278512 Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity 45 samples shares maturation, promotes
- GSE286357 Transcriptional regulation of temporal dynamics in human neurogenesis and neuronal maturation [scRNA-seq] 35 samples shares maturation, scrna-seq
- GSE283775 Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity followed by gradual electrochemical maturation [scRNA-seq] 14 samples shares maturation, scrna-seq
- GSE289735 Alpha-ketoglutarate -mediated carnitine synthesis promotes homologous recombination via histone acetylation 12 samples shares ketoglutarate, promotes
- GSE275610 scRNA-seq and snATAC-seq reveal differentiation trajectories of several pancreatic islet induction protocols 341 samples shares induction, scrna-seq
- GSE244721 Human trophectoderm becomes multi-layered by internalization at the polar region 268 samples shares trophectoderm
- GSE211875 Affinity maturation broadens influenza vaccine-induced antibody responses in humans 247 samples shares maturation
- GSE211869 Affinity maturation broadens influenza vaccine-induced antibody responses in humans [bcr] 128 samples shares maturation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.