Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity followed by gradual electrochemical maturation [scRNA-seq]
Single-cell RNA-seq · human · 14 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 14 samples: 14 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283775_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1195570 and SRA study SRP550057. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 14 sample titles: 14 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8672150 200319S,EOPs,batch 1
- GSM8672151 010519S1,EOPs,batch 2
- GSM8672152 010519S2,EOPs,batch 3
- GSM8672153 111219S,EOPs,batch 4
- GSM8672154 251219S,EOPs,batch 5
- GSM8672155 150120S,EOPs,batch 6
- GSM8672156 200520S1,EOPs,batch 7
- GSM8672157 200520S2,EOPs,batch 8
- GSM8672158 100620S,EOPs,batch 9
- GSM8672159 010720S,EOPs,batch 10
- GSM8672160 220720S1,EOPs,batch 11
- GSM8672161 220720S2,EOPs,batch 12
- GSM8672162 070120S,EOPs,batch 13
- GSM8672163 280120S,EOPs,batch 14
- GSE283776 Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity followed by gradual electrochemical maturation [snRNA-seq] 19 samples shares electrochemical, cell-derived, interneuron, maturation, gabaergic, emergence, diversity
- GSE286357 Transcriptional regulation of temporal dynamics in human neurogenesis and neuronal maturation [scRNA-seq] 35 samples shares maturation, scrna-seq
- GSE249826 Human-induced pluripotent Stem Cell-Derived Hepatic Stellate Cells in Liver Organoids: Maturation Promotion and Essential Role in Vascularization 26 samples shares cell-derived, maturation
- GSE268981 Graphene-polymer nanofibers enable optically induced electrical maturation in stem cell-derived cardiomyocytes and brain organoids 23 samples shares cell-derived, maturation
- GSE326651 in vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures [day0NMP_bulk RNAseq] 15 samples shares cell-derived, interneuron
- GSE326655 in vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures [day43NMP_scRNAseq] 12 samples shares cell-derived, interneuron
- GSE336395 Multi-omic analysis reveals maturation programs in human pluripotent stem cell-derived cardiomyocytes during long-term culture 11 samples shares cell-derived, maturation
- GSE262419 Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes 4558 samples shares cell-derived
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.