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RNA Surveillance Maintained by the RNA Helicase MTR4 Determines the Large Volume of Mouse Oocytes [ATAC-seq]

GSE247846 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/09/09 Platform GPL24247
Summary
Exosome is the main RNA surveillance and degradation pathway during oocyte growth. To figure out specific roles of RNA surveillance in oocyte growth, the pathway was destroied by deleting MTR4, the only known RNA helicase in exosome pathway. Accumulation of waste RNAs in nucleus seriously effect chromatin status and NSN-SN transition. Thus ATAC-seq experiments were performed to get a better review for chromatin status.
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Direct links to NCBI, no account and no request form: the whole study as GSE247846_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1010991 and SRA study SRP457673. Searching any of these in the dataset finder brings you back here.

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