Differences in gene expression between myxoid liposarcoma and Ewing sarcoma cell lines
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Ewing sarcomaThis series is part of our curated briefing on it.
- Samples
- 20 samples: 5 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248354_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1043580 and SRA study SRP473219. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 5 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7911937 EWS 6647 p2 EWS 6647 p
- GSM7911938 EWS 6647 p3 EWS 6647 p
- GSM7911939 EWS 6647 p5 EWS 6647 p
- GSM7911940 EWS 6647 p6 EWS 6647 p
- GSM7911941 EWS TC-71 p2 EWS TC-71 p
- GSM7911942 EWS TC-71 p3 EWS TC-71 p
- GSM7911943 EWS TC-71 p4 EWS TC-71 p
- GSM7911944 EWS TC-71 p6 EWS TC-71 p
- GSM7911945 MLS 1765-92 p3 MLS 1765-92 p
- GSM7911946 MLS 1765-92 p4 MLS 1765-92 p
- GSM7911947 MLS 1765-92 p5 MLS 1765-92 p
- GSM7911948 MLS 1765-92 p6 MLS 1765-92 p
- GSM7911949 MLS 402-91 p2 MLS 402-91 p
- GSM7911950 MLS 402-91 p3 MLS 402-91 p
- GSM7911951 MLS 402-91 p4 MLS 402-91 p
- GSM7911952 MLS 402-91 p5 MLS 402-91 p
- GSM7911953 MLS 2645-94 p2 MLS 2645-94 p
- GSM7911954 MLS 2645-94 p3 MLS 2645-94 p
- GSM7911955 MLS 2645-94 p4 MLS 2645-94 p
- GSM7911956 MLS 2645-94 p6 MLS 2645-94 p
- GSE235218 Differential chromatin landscape in myxoid liposarcoma and Ewing sarcoma 6 samples same disease briefing · shares liposarcoma, sarcoma, myxoid, ewing
- GSE289118 New Cell lines Expanding the Diversity of Ewing Sarcoma Models 44 samples same disease briefing · shares sarcoma, ewing, lines
- GSE229906 Chimeric protein EWS::FLI1 drives cell proliferation in Ewing Sarcoma via aberrant expression of KCNN1/SK1 and dysregulation of calcium signaling 45 samples same disease briefing · shares sarcoma, ewing
- GSE332586 Mevalonate pathway activation in Ewing sarcoma reveals a 3D-specific synergy between statins and BCL-xL inhibition 36 samples same disease briefing · shares sarcoma, ewing
- GSE272957 EWSR1/FLI1 Expression in Human Mesenchymal Stem Cells derived from Experimental Teratomas Leads to Ewing´s Sarcoma Tumorigenesis [RNA-seq] 16 samples same disease briefing · shares sarcoma, ewing
- GSE311851 LSD1 Performs Demethylase-Independent and Context-Specific Roles in Ewing Sarcoma 114 samples same disease briefing · shares sarcoma, ewing
- GSE263430 Effect of HOXC6 deletion on gene expression in Ewing Sarcoma cell line RD-ES. 9 samples same disease briefing · shares sarcoma, ewing
- GSE299137 Autocrine TGFβ2 enforces a transcriptionally hybrid cell state in Ewing sarcoma 48 samples same disease briefing · shares sarcoma, ewing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.