RNA helicase DDX5 maintains cardiac function by regulating CamkIIδ alternative splicing [RNA-seq]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × mCKO_Heart_8w vs 3 × CTR1_Heart_8w vs 3 × iCKO_Heart vs 3 × CTR2_HeartGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- RNA Helicase DDX5 Maintains Cardiac Function by Regulating CamkIIδ Alternative SplicingCirculation · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248443_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1044023 and SRA study SRP473671. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7914443 mCKO_Heart_8w_1 mCKO_Heart_8w
- GSM7914444 mCKO_Heart_8w_2 mCKO_Heart_8w
- GSM7914445 mCKO_Heart_8w_3 mCKO_Heart_8w
- GSM7914446 CTR1_Heart_8w_1 CTR1_Heart_8w
- GSM7914447 CTR1_Heart_8w_2 CTR1_Heart_8w
- GSM7914448 CTR1_Heart_8w_3 CTR1_Heart_8w
- GSM7914449 iCKO_Heart_1 iCKO_Heart
- GSM7914450 iCKO_Heart_2 iCKO_Heart
- GSM7914451 iCKO_Heart_3 iCKO_Heart
- GSM7914452 CTR2_Heart_1 CTR2_Heart
- GSM7914453 CTR2_Heart_2 CTR2_Heart
- GSM7914454 CTR2_Heart_3 CTR2_Heart
- GSE336247 Cardiac fibroblast deletion of PTBP1 modulates the profibrotic response by alternative splicing II 36 samples shares alternative, splicing, cardiac
- GSE287133 Cardiac fibroblast deletion of PTBP1 modulates the profibrotic response by alternative splicing. 12 samples shares alternative, splicing, cardiac
- GSE286904 Persistent large-scale changes in alternative splicing in prefrontal cortical neuron types following psychedelic exposure 118 samples shares alternative, splicing
- GSE328655 A high-resolution, sex-stratified atlas of transcriptional and alternative splicing dynamics in the fasting mouse liver. 80 samples shares alternative, splicing
- GSE242179 Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification 40 samples shares alternative, splicing
- GSE228599 High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters 34 samples shares alternative, splicing
- GSE325918 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [RNA-seq] 32 samples shares regulating, rna-seq
- GSE296482 A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains homeostatic Th17 cell state [RNA-seq] 31 samples shares maintains, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.