Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma
Expression microarray · mouse · 26 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248615_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA1045040 and SRA study SRP474152. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 26 samples.
How we read this: 8 replicated groups read from 26 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7917949 WT_rep 1 WT
- GSM7917950 WT_rep 2 WT
- GSM7917951 WT_rep 3 WT
- GSM7917952 K14-SCF_rep 1 K14-SCF
- GSM7917953 K14-SCF_rep 2 K14-SCF
- GSM7917954 K14-SCF_rep 3 K14-SCF
- GSM7917955 Young_telogen_rep 1 Young_telogen
- GSM7917956 Young_telogen_rep 2 Young_telogen
- GSM7917957 Young_telogen_rep 3 Young_telogen
- GSM7917958 Young_early anagen_rep 1 Young_early anagen
- GSM7917959 Young_early anagen_rep 2 Young_early anagen
- GSM7917960 Young_early anagen_rep 3 Young_early anagen
- GSM7917961 Old_telogen_rep 1 Old_telogen
- GSM7917962 Old_telogen_rep 2 Old_telogen
- GSM7917963 Old_telogen_rep 3 Old_telogen
- GSM7917964 Old_early anagen_rep 1 Old_early anagen
- GSM7917965 Old_early anagen_rep 2 Old_early anagen
- GSM7917966 Old_early anagen_rep 3 Old_early anagen
- GSM7992563 Young_rep 1 Young
- GSM7992564 Young_rep 2 Young
- GSM7992565 Young_rep 3 Young
- GSM7992566 Young_rep 4 Young
- GSM7992567 Old_rep 1 Old
- GSM7992568 Old_rep 2 Old
- GSM7992569 Old_rep 3 Old
- GSM7992570 Old_rep 4 Old
- GSE248614 Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma [RNA-seq] 12 samples shares antagonistic, decisions, melanoma, greying, stress, govern, fates, stem
- GSE270324 The integrated stress response fine-tunes stem cell fate decisions in response to serine deprivation and tissue injury [RNA-seq] 2 samples shares decisions, stress, stem
- GSE244780 Redox Heterogeneity in Mouse Embryonic Stem Cells Individualizes Cell Fate Decisions 33 samples shares decisions, stem
- GSE244777 Redox Heterogeneity in Mouse Embryonic Stem Cells Individualizes Cell Fate Decisions I 27 samples shares decisions, stem
- GSE197791 Transdermal nanolipoplex simultaneously inhibits subcutaneous melanoma growth and suppresses systemically metastatic melanoma by activating host immunity 15 samples shares melanoma, stem
- GSE215963 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma. 1497 samples shares melanoma
- GSE215959 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma [M4_aCTLA4_scRNA] 1248 samples shares melanoma
- GSE215960 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma [scRNA-seq] 192 samples shares melanoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.