GEO series
scRNA-seq of CD4+ T cells from mouse allergic airway inflammation model and human patients with eosinophilic chronic rhinosinusitis (ECRS)
GSE249159
Homo sapiens; Mus musculus
Expression profiling by high throughput sequencing
10 samples
2025/10/24
GPL24676GPL24247
Summary
A unique subpopulation of memory Th2 cells expressing the interleukin-33 receptor ST2 contributes to the pathogenesis of allergic diseases; however, the immune-metabolic mechanisms that induce ST2hi memory Th2 cells in inflamed tissues remain uncertain. Using single-cell RNA-sequencing (scRNA-seq), we revealed active lipid storage and catabolism during ST2hi memory Th2 cell induction in inflamed murine lungs and nasal polyps from patients with ECRS.
Download
NCBI GEO page ↗
Paper (PMID 41134875) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
RNA-seq datasets →
Similar datasets
- GSE301111 Dissecting cellular state alterations critical for the synergistic response and therapy resistance of the combined Abemaciclib, Temozolomide, and Radiation in DIPG PDOX models 14 samples
- GSE274229 Evolution of myeloid-mediated immunotherapy resistance in prostate cancer 52 samples
- GSE289420 Astrocyte-derived cholesterol drives synaptic gene expression in developing neurons and reciprocal astrocytic transcriptional programs 416 samples
- GSE342640 Insulin resistance is associated with mammary mitochondrial dysfunction at the onset of human lactation 159 samples
- GSE341321 Vitamin B2 Sensing by the Nuclear Receptor AhR Reprograms Hepatic Metabolism [RNA-Seq] 100 samples
- GSE253849 Human and mouse adrenal glands are characterized by species-specific steroidogenic states and tissue turnover [scRNA-seq] 22 samples
- GSE195453 Identification of the endothelial cell microproteome. 121 samples
- GSE317309 Combination of a CCL21-gene modified dendritic cell vaccine and pembrolizumab induces immune responses in non-small cell lung cancer 64 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.