Hepatic leukemia factor directs tissue residency of proinflammatory CD4+ T cells
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 22 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 22 samples: 5 × ECRS_PBMC vs 5 × ECRS_Polyp vs 2 × scRNA_7w_Asp_ivnega vs 2 × scRNA_7w_Asp_ivposiGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Hepatic leukemia factor directs tissue residency of proinflammatory memory CD4(+) T cellsScience (New York, N.Y.) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295436_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1254670 and SRA study SRP580812. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 4 replicated groups read from 22 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8948071 scRNA_7w_Asp_ivnega_rep1 scRNA_7w_Asp_ivnega
- GSM8948072 scRNA_7w_Asp_ivnega_rep2 scRNA_7w_Asp_ivnega
- GSM8948073 scRNA_7w_Asp_ivposi_rep1 scRNA_7w_Asp_ivposi
- GSM8948074 scRNA_7w_Asp_ivposi_rep2 scRNA_7w_Asp_ivposi
- GSM8948075 scRNA_Control_ivnega
- GSM8948076 scRNA_Control_ivposi
- GSM8948077 scRNA_14w_Asp_ivnega
- GSM8948078 scRNA_14w_Asp_ivposi
- GSM8948079 scATAC_7w_Asp_ivnega
- GSM8948080 scATAC_7w_Asp_ivposi
- GSM8948081 scATAC_Control_ivnega
- GSM8948082 scATAC_Control_ivposi
- GSM8948083 ECRS_PBMC_1 ECRS_PBMC
- GSM8948084 ECRS_Polyp_1 ECRS_Polyp
- GSM8948085 ECRS_PBMC_2 ECRS_PBMC
- GSM8948086 ECRS_Polyp_2 ECRS_Polyp
- GSM8948087 ECRS_PBMC_3 ECRS_PBMC
- GSM8948088 ECRS_Polyp_3 ECRS_Polyp
- GSM8948089 ECRS_PBMC_4 ECRS_PBMC
- GSM8948090 ECRS_Polyp_4 ECRS_Polyp
- GSM8948091 ECRS_Polyp_5 ECRS_Polyp
- GSM8948092 ECRS_PBMC_5 ECRS_PBMC
- GSE239704 NF-κB transcription factors RelA and c-Rel selectively control CD4+ T-cell function in multiple sclerosis and cancer 34 samples shares cd4, factor
- GSE236107 Single cell transcriptomic analysis of acute and early ART-treated HIV-1-infected CD4+T cells from a reservoir-marking humanized mouse model 14 samples shares cd4
- GSE292898 Isolation and characterization of an islet-associated CD45- MHC class II+ cells using single cell RNA sequencing. 11 samples shares cd4
- GSE249159 scRNA-seq of CD4+ T cells from mouse allergic airway inflammation model and human patients with eosinophilic chronic rhinosinusitis (ECRS) 10 samples shares cd4
- GSE261475 Engineered CD47 protects T cells for enhanced antitumor immunity 8 samples shares cd4
- GSE253753 Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia 126 samples shares leukemia
- GSE295715 Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness 90 samples shares leukemia
- GSE248326 The catalytic domain of SETD1B regulates H3K4me3 breadth and Myc expression in MLL-r leukemia 53 samples shares leukemia
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.