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Neutrophils stimulation with AVP promote IL36G release

GSE249379 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/01 Platform GPL24247
Summary
We found that neutrophils were homing back to bone marrow and induced myelopoiesis after AVP treatment.This study investigated how neutrophils promoted HSC differentiation by comparing the expression of genes between control and AVP treatment neutrophils.We demonstrated that AVP treatment increased the expression of a variety of cytokine genes, especially IL36G, and the augmentation of bone marrow myelopoiesis involves IL36G-IL1RL2 axis.
Published in
Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice
Mou R, Ma J, Ju X et al. · Cell stem cell 2024 · PMID 39442524 · doi:10.1016/j.stem.2024.09.018
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Also filed as BioProject PRJNA1048924 and SRA study SRP476043. Searching any of these in the dataset finder brings you back here.

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