GEO series
Discerning the roles of key cytokine signaling pathways in DR Mtb infection [dataset1]
GSE249400
Mus musculus
Expression profiling by high throughput sequencing
20 samples
2024/04/03
GPL24247
Summary
We have found that drug-resistant (DR) Mtb infection alters the host pathogen interactions thought to occur during drug-sensitive (DS) Mtb infection. Recent data suggests that lack of both, Type I and IL-1, signaling pathways leads to susceptibility to infection to DR Mtb infection. To understand the pathways involved in maintaining control of DR Mtb infection, we are sequencing the bulk lung cells early in infection.
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Paper (PMID 38603763) ↗
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