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Surface CD52, CD84 and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors [scRNA-seq]

GSE250001 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/03/07 Platform GPL18573
Summary
In this study, we reported the identification of a specific gene signature expressed by mPMN-MDSCs from NSCLC/HNC patients and G-CSF-treated donor (GDs) by bulk-RNA-seq that clearly reflects their metabolic/functional reprogramming. ScRNA-seq experiments further confirmed that the mPMN-MDSC gene signature is significantly enriched in both mNDNs/mLDNs from GDs
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Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors
Pettinella F, Mariotti B, Lattanzi C et al. · Cell reports. Medicine 2024 · PMID 38242120 · doi:10.1016/j.xcrm.2023.101380
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Also filed as BioProject PRJNA1051589 and SRA study SRP477607. Searching any of these in the dataset finder brings you back here.

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