Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in mouse utricle
RNA-seq (gene expression) · mouse · 57 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 57 samples: 49 distinct titles, 6 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in the mature mouse utricleNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE251854_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1055553 and SRA study SRP455086. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 57 sample titles: 49 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7710365 Explant, CMV-ATOH1, day 7, rep1
- GSM7710366 Explant, GFAP-ATOH1, day 7, rep1
- GSM7710367 Explant, CMV-ATOH1, day 12, rep1
- GSM7710368 Explant, GFAP-ATOH1, day 12, rep1
- GSM7710369 Explant, CMV-ATOH1, day 12, rep2
- GSM7710370 Explant, GFAP-ATOH1, day 12, rep2
- GSM7710371 Explant, RLBP1-ATOH1, day 12, rep1
- GSM7710372 Explant, CMV-ATOH1, day 12, rep3
- GSM7710373 Explant, CMV-ATOH1, day 20, rep1
- GSM7710374 Explant, GFAP-ATOH1, day 12, rep3
- GSM7710375 Explant, GFAP-ATOH1, day 20, rep1
- GSM7710376 Explant, RLBP1-ATOH1, day 12, rep2
- GSM7710377 Explant, RLBP1-ATOH1, day 20, rep1
- GSM7710378 In vivo cristae, GFAP-ATOH1, 2wk
- GSM7710379 In vivo cristae, IDPN only, 2wk
- GSM7710380 In vivo cristae, Untreated, 2wk
- GSM7710381 In vivo utricle, GFAP-ATOH1, 2wk
- GSM7710382 In vivo utricle, IDPN only, 2wk
- GSM7710383 In vivo utricle, Untreated, 2wk
- GSM7710384 In vivo cristae, GFAP-ATOH1, 4wk, rep1
- GSM7710385 In vivo cristae, IDPN only, 4wk, rep1
- GSM7710386 In vivo cristae, Untreated, 4wk
- GSM7710387 In vivo utricle, IDPN only, 4wk, rep1
- GSM7710388 In vivo utricle, IDPN only, 4wk, rep2
- GSM7710389 In vivo utricle,GFAP-ATOH1, 4wk
- GSM7710390 In vivo cristae, IDPN only, 4wk, rep2
- GSM7710391 In vivo cristae, GFAP-ATOH1, 4wk, rep2
- GSM7989111 S63_E15_Ut
- GSM7989112 S63_E18_Ut
- GSM7989113 S63_P1_Ut
- GSM7989114 S63_P12_Ut
- GSM7989115 S63_P6_ut
- GSM7989116 S80_E16_utA
- GSM7989117 S80_E16_utB
- GSM7989118 S80_E18_utA
- GSM7989119 S80_E18_utB
- GSM7989120 S80_P0_utA
- GSM7989121 S80_P0_utB
- GSM7989122 S80_P1_utA
- GSM7989123 S80_P1_utB
+ 17 more — browse all 57 samples with per-sample file links →
- GSE298416 Biomimetic fractal topography enhances podocyte maturation in vitro 17 samples shares maturation, enhances
- GSE293383 Viscoelastic Extracellular Matrix Enhances Epigenetic Remodeling and Cellular Plasticity [RNA-seq] 12 samples shares enhances, genetic
- GSE269184 Dynamic expression of Erg controls fetal-to-adult maturation of the hematopoietic system [RNA-seq] 12 samples shares maturation, control
- GSE205438 RNA splicing controls organ-wide maturation of postnatal heart in mice 88 samples shares maturation, control
- GSE287123 Regulated somatic hypermutation enhances antibody affinity maturation 27 samples shares maturation, enhances
- GSE67857 Host microbiota constantly control maturation and function of microglia in the central nervous system (part 2) 20 samples shares maturation, control
- GSE249591 Gene suppression by PRC2 enhances the gene inductions by Aire and the development of mimetic cell populations 572 samples shares enhances
- GSE318351 IL1A enhances TNF-induced retinal ganglion cell death 109 samples shares enhances
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.