Dynamic expression of Erg controls fetal-to-adult maturation of the hematopoietic system [RNA-seq]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × rnaseq_Tg_BM vs 4 × rnaseq_WT_BM vs 4 × rnaseq_WT_FLGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Dynamic activity of Erg promotes maturation of the hematopoietic systemBlood advances · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269184_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1120472 and SRA study SRP512055. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8307742 rnaseq_Tg_BM1 rnaseq_Tg_BM
- GSM8307743 rnaseq_Tg_BM2 rnaseq_Tg_BM
- GSM8307744 rnaseq_Tg_BM3 rnaseq_Tg_BM
- GSM8307745 rnaseq_Tg_BM4 rnaseq_Tg_BM
- GSM8307746 rnaseq_WT_BM1 rnaseq_WT_BM
- GSM8307747 rnaseq_WT_BM2 rnaseq_WT_BM
- GSM8307748 rnaseq_WT_BM3 rnaseq_WT_BM
- GSM8307749 rnaseq_WT_BM4 rnaseq_WT_BM
- GSM8307750 rnaseq_WT_FL1 rnaseq_WT_FL
- GSM8307751 rnaseq_WT_FL2 rnaseq_WT_FL
- GSM8307752 rnaseq_WT_FL3 rnaseq_WT_FL
- GSM8307753 rnaseq_WT_FL4 rnaseq_WT_FL
- GSE265909 yHSC and oHSC scRNAseq with oHSC AThi ATlo Index Sorting. Assessing the transcriptional changes associated with autophagy engagement in old hematopoietic stem cells at single cell resolution. [scRNA-Seq] 563 samples shares hematopoietic, rna-seq
- GSE310620 RNA-seq in aortic smooth muscle cells from a mice lacking Arg1 expression in erytrhrocytes (RBC.ARG1-KO) and their litter mate controls (RBC.ARG1-WT) after culture in standard DMEM or foam cell medium (DIAM) 16 samples shares controls, rna-seq
- GSE288210 Comparative gene expression profiling of RNA-seq data from islets of β-cell-specific ZZEF1 knockout mice (βZKO-Mip) and their littermate controls, treated with either azoramide or DMSO. 11 samples shares controls, rna-seq
- GSE266509 A Bcl11a-driven mechanism maintaining hematopoietic stem cell functionality gives rise to dysfunction during aging [RNA-Seq] 52 samples shares hematopoietic, rna-seq
- GSE240857 Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner[RNA-Seq] 29 samples shares maturation, rna-seq
- GSE276137 The ac4C acetyltransferase Nat10 promotes RNA stability to support hematopoietic stem cell fate [RNA-seq-32D] 24 samples shares hematopoietic, rna-seq
- GSE310548 Distinct contributions of Etv2+ and Flk1+ progenitors to endothelial, hematopoietic, and cardiac lineages [RNA-seq] 21 samples shares hematopoietic, rna-seq
- GSE271650 Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes [bulk RNA-seq] 18 samples shares controls, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.