Human and mouse adrenal glands are characterized by species-specific steroidogenic states and tissue turnover
RNA-seq (gene expression) · mouse · 31 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 31 samples: 31 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE253852_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1067561 and SRA study SRP485201. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 31 sample titles: 31 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8028731 Human_adult_adrenal_Female_18_years, healthy adult, scRNAseq
- GSM8028732 Human_adult_adrenal_Female_53_years_1, healthy adult, scRNAseq
- GSM8028733 Human_adult_adrenal_Female_53_years_2, healthy adult, scRNAseq
- GSM8028734 Human_adult_adrenal_Female_59_years, healthy adult, scRNAseq
- GSM8028735 Human_adult_adrenal_Female_64_years, healthy adult, scRNAseq
- GSM8028736 Human_adult_adrenal_Male_39_years, healthy adult, scRNAseq
- GSM8028737 Human_adult_adrenal_Male_48_years, healthy adult, scRNAseq
- GSM8028738 Human_adult_adrenal_Male_52_years, healthy adult, scRNAseq
- GSM8028739 Human_adult_adrenal_Male_54_years, healthy adult, scRNAseq
- GSM8028740 Human_adult_adrenal_Male_57_years, healthy adult, scRNAseq
- GSM8028741 Human_adult_adrenal_Male_73_years, healthy adult, scRNAseq
- GSM8028742 Mouse_adult_adrenal_Female_1, healthy adult, scRNAseq
- GSM8028743 Mouse_adult_adrenal_Female_2, healthy adult, scRNAseq
- GSM8028744 Mouse_adult_adrenal_Female_3, healthy adult, scRNAseq
- GSM8028745 Mouse_adult_adrenal_Female_4, healthy adult, scRNAseq
- GSM8028746 Mouse_adult_adrenal_Female_5, healthy adult, scRNAseq
- GSM8028747 Mouse_adult_adrenal_Mixed_1, healthy adult, scRNAseq
- GSM8028748 Mouse_adult_adrenal_Male_1, healthy adult, scRNAseq
- GSM8028749 Mouse_adult_adrenal_Male_2, healthy adult, scRNAseq
- GSM8028750 Mouse_adult_adrenal_Male_3, healthy adult, scRNAseq
- GSM8028751 Mouse_adult_adrenal_Male_4, healthy adult, scRNAseq
- GSM8028752 Mouse_adult_adrenal_Male_5, healthy adult, scRNAseq
- GSM8028753 Human_adult_adrenal_Male_52_years, healthy adult, Visium A1
- GSM8028754 Human_adult_adrenal_Female_61_years, healthy adult, Visium B1
- GSM8028755 Human_adult_adrenal_Male_21_years, healthy adult, Visium C1
- GSM8028756 Human_adult_adrenal_Female_19_years, healthy adult, Visium D1
- GSM8874474 Mouse_adult_adrenal_Male, healthy adult, Visium HD A1
- GSM8874475 Mouse_adult_adrenal_Female, healthy adult, Visium HD D1
- GSM8874476 Human_adult_adrenal_Female_20_years, healthy adult, Stereo-seq
- GSM8874477 Human_adult_adrenal_Male_13_years, healthy adult, Stereo-seq
- GSM8874478 Human_adult_adrenal_Male_40_years, healthy adult, Stereo-seq
- GSE86336 m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover 20 samples shares turnover
- GSE324846 Developmental gene expression patterns driving species-specific cortical features 17 samples shares species-specific
- GSE245373 Mice are not men: scRNA-sequencing of the human atherosclerotic plaque identifies species-specific immune cell phenotypes that associate with clinical disease 11 samples shares species-specific
- GSE270069 Species-specific progenitor domain extends neurogenesis and increases motor neuron production 3 samples shares species-specific
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.