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Comparison of ILC1s and NK cells transcriptomes in subcutaneous tumor model

GSE253918 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/08/28 Platform GPL23479
Summary
ILC1s are tissue-resident lymphocytes, their recruitment, migration and infiltration into subcutaneous tumors is a big concern. In addition, as NK cells and ILC1s are phenotypically similar, it is difficult to assess the relative contribution of these two cell types to anti-tumor function. Here, we compared the transcriptomes of ILC1s and NK cells from MC38 tumor-bearing mice to understand the biological/phenotypic changes of ILC1s.
Published in
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity
Yan J, Zhang C, Xu Y et al. · Nature immunology 2024 · PMID 39358444 · doi:10.1038/s41590-024-01973-z
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Direct links to NCBI, no account and no request form: the whole study as GSE253918_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1067665 and SRA study SRP485284. Searching any of these in the dataset finder brings you back here.

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