CXCL10 and IFN-γ Mediate Myocarditis Post-COVID19 mRNA Vaccination [mouse]
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254538_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1070998 and SRA study SRP486718. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8045667 Mouse_heart_Cntrol_1 [CON1]
- GSM8045668 Mouse_heart_Cntrol_2 [CON2]
- GSM8045669 Mouse_heart_Cntrol_3 [CON3]
- GSM8045670 Mouse_heart_Cntrol_4 [CON4]
- GSM8045671 Mouse_heart_Cntrol_5 [CON5]
- GSM8045672 Mouse_heart_Cntrol_6 [CON6]
- GSM8045673 Mouse_heart_Cytokine_1 [CYT1]
- GSM8045674 Mouse_heart_Cytokine_2 [CYT2]
- GSM8045675 Mouse_heart_Cytokine_3 [CYT3]
- GSM8045676 Mouse_heart_Cytokine_4 [CYT4]
- GSM8045677 Mouse_heart_Cytokine_5 [CYT5]
- GSM8045678 Mouse_heart_Cytokine_6 [CYT6]
- GSM8045679 Mouse_heart_Genistein_1 [GEN1]
- GSM8045680 Mouse_heart_Genistein_2 [GEN2]
- GSM8045681 Mouse_heart_Genistein_3 [GEN3]
- GSM8045682 Mouse_heart_Genistein_4 [GEN4]
- GSM8045683 Mouse_heart_Genistein_5 [GEN5]
- GSM8045684 Mouse_heart_Genistein_6 [GEN6]
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- GSE337186 IFNg and IFNg mimetics prevent IFN-I-mediated TB susceptibility by regulating iron metabolism and lipid peroxidation. 24 samples shares ifn, mediate
- GSE278131 TBK1 and IKKε protect target cells from IFNgamma-mediated inflammatory apoptosis 18 samples shares ifn, mediate
- GSE290553 How infection impacts regulation of adipocyte metabolism and does IFNγ directly targets adipocytes and mediates lipid metabolism in vivo following infection 16 samples shares ifn, mediate
- GSE237643 Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2- dependent transcription of Ifng 58 samples shares ifn, mrna
- GSE280326 Targeting Vdac2 enables IFN gamma-mediated destruction and inflammatory remodeling of tumors to overcome immune evasion [ATAC-seq 1] 16 samples shares ifn, mediate
- GSE261309 Macrophages suppress cardiac reprogramming of fibroblasts in vivo via IFN-mediated intercellular self-stimulating circuit 11 samples shares ifn, mediate
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.