← BioTransfer GEO Dataset Finder
GEO series

Gene expression analysis of enzalutamide resistant MDA PCa 2b prostate cancer cells

GSE254612 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/09/26 Platform GPL24676
Summary
MDA PCa 2b is an androgen-responsive, AR-positive prostate cancer cell line. Here, we report the generation of an Enzalutamide-resistant derivative, MDA PCa 2b-EnzaR. Gene expression of MDA PCa 2b-EnzaR compared to its parental counterpart were assessed by short-read RNA sequencing.
Published in
Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression
Van Goubergen J, Peřina M, Handle F et al. · Molecular oncology 2025 · PMID 39258426 · doi:10.1002/1878-0261.13728
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE254612_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1071136 and SRA study SRP486901. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.