GEO series
The effects of a low isoleucine diet on the liver expression of aged C57BL/6J.Nia mice of both sexes
GSE254721
Mus musculus
Expression profiling by high throughput sequencing
36 samples
2024/09/17
GPL24247
Summary
Dietary isoleucine is a significant determinant of metabolic health and longevity. In this study, we found that even at an advanced age, both male and female mice received significant metabolic benefits from a low isoleucine diet. We collected liver tissues for transcriptomic analysis and the results found that the majority of age-driven changes is ameliorated with the administration of low isoleucine diet.
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Paper (PMID 39604703) ↗
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