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Expression profile of 22Rv1 cells with GFP or HNF4G exogenous expression when treated with BETi ABBV-075

GSE254733 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2025/01/18 Platform GPL24676
Summary
To study the consequence of HNF4G target genes expression with ABBV-075 treatment in cells that have BETi-independent HNF4G expression, we performed RNA-Seq on 22Rv1 cells that exogenously express HNF4G using GFP expression as control.
Published in
BET inhibitors reduce tumor growth in preclinical models of gastrointestinal gene signature-positive castration-resistant prostate cancer
Shukla S, Li D, Cho WH et al. · The Journal of clinical investigation 2025 · PMID 40553565 · doi:10.1172/JCI180378
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Also filed as BioProject PRJNA1071591 and SRA study SRP487172. Searching any of these in the dataset finder brings you back here.

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