Splicing targeting approaches highlight actionable vulnerabilities in triple negative breast cancer

Direct links to NCBI, no account and no request form: the whole study as GSE254842_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1072064 and SRA study SRP487495. Searching any of these in the dataset finder brings you back here.

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• GSE328275 Single-cell RNA sequencing of CD45+ immune cells across primary tumor, sentinel tumor-draining lymph node, and axillary lymph node in treatment-naive triple-negative breast cancer 28 samples
• GSE303346 Single-Cell RNA-Seq Reveals Immunosuppressive Effects of Triple-Negative Breast Cancer–Derived Exosomes on NK Cell Responses 16 samples
• GSE319641 RNA-Seq profiling of pre- and on-treatment tumor samples from breast cancer patients enrolled in the NeoTRIP trial. 401 samples
• GSE323973 Expression profiling by high throughput sequencing of breast cancer 158 samples
• GSE303509 Biomarker-guided responses in patient-derived organoids predict effective therapies in breast cancer 14 samples
• GSE342455 Transcriptomic profiling of tumor-associated macrophages following pharmacological SYK inhibition in a human breast cancer co-culture model 6 samples
• GSE243013 A single-cell atlas of immune heterogeneity in anti-PD1-treated non-small cell lung cancer 243 samples
• GSE309841 Integrative tissue analysis of men with prostate cancer VIII 42 samples

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