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RNA-seq analysis of differentially expressed genes between WT and shTRIM21 RKO cells.

GSE254956 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/08/22 Platform GPL24676
Summary
To investigate the biological function TRIM21 in the colorectal cancer, we established RKO cell lines in which the TRIM21 gene has been knocked down by shRNA. We used a lentiviral shRNA technique to knockdown TRIM21 expression in RKO cells. A scrambled shRNA (shRNA/Control) was used as a control. We then performed RNA-Seq with Cloud-seq Biotech Inc. (Shanghai, China) to analyze gene expression changes in RKO cells. For each sample, three independent biological replicates were performed.
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Also filed as BioProject PRJNA1072702 and SRA study SRP487834. Searching any of these in the dataset finder brings you back here.

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