GEO series
Transcriptional profiling of lungs from SARS-CoV-2-infected K18-hACE2 mice
GSE254969
Mus musculus
Expression profiling by high throughput sequencing
15 samples
2025/02/01
GPL21626
Summary
To explore the effects of SARS-CoV-2 proteins on expression of host genes in lung of infected mice, 4 groups of K18-hACE2 mice (4 mice per group) were mock-infected or infected cells with SARS-CoV-2 WT or its NPS1, or NSP15 mutants respectively.The mice were euthanized at 4 days post-infection to collect the lungs to isolate RNA for RNA sequencing.
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Paper (PMID 42160380) ↗
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