GEO series
Transcriptomic profiling of peroxisome-deficient, myelin debris-laden macrophages
GSE255159
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2024/12/31
GPL24247
Summary
Study objective was to investigate the molecular underpinnings of how Pex5 and peroxisome integrity facilitated the demyelination response in myeloid cells. We investigated the transcriptomic changes related to myelin debris uptake in the context of disrupted peroxisome integrity using Pex5 deficient bone marrow derived macrophages.
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Paper (PMID 41196656) ↗
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