Effect of Low-dose-rate Radiation on Cognition and Gene Expression Profiles in Type II Diabetes Mellitus Mouse Model
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × B6 0 Gy vs 3 × db/db 0 Gy vs 3 × db/db 0.1 Gy vs 3 × db/db 2 GyGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Effect of Low-Dose-Rate Radiation on Cognition and Gene Expression Profiles in Type II Diabetes Mellitus Mouse ModelMolecular neurobiology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE255433_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1075032 and SRA study SRP489097. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8072380 B6 0 Gy-1 B6 0 Gy
- GSM8072381 B6 0 Gy-2 B6 0 Gy
- GSM8072382 B6 0 Gy-3 B6 0 Gy
- GSM8072383 db/db 0 Gy-1 db/db 0 Gy
- GSM8072384 db/db 0 Gy-2 db/db 0 Gy
- GSM8072385 db/db 0 Gy-3 db/db 0 Gy
- GSM8072386 db/db 0.1 Gy-1 db/db 0.1 Gy
- GSM8072387 db/db 0.1 Gy-2 db/db 0.1 Gy
- GSM8072388 db/db 0.1 Gy-3 db/db 0.1 Gy
- GSM8072389 db/db 2 Gy-1 db/db 2 Gy
- GSM8072390 db/db 2 Gy-2 db/db 2 Gy
- GSM8072391 db/db 2 Gy-3 db/db 2 Gy
- GSE302019 Bulk RNA sequencing to investigate transcriptional profiles of lung macrophage subpopulations isolated from wild-type C57BL/6J and Spp1-EGFP knock-in reporter mice subjected to intratracheal administration of bleomycin or PBS. 24 samples shares profiles, type
- GSE303725 Effects of attenuating astrocytic Ca2+ activity in the medial prefrontal cortex with iβARK on transcriptional profiles in wild-type mice. 17 samples shares profiles, type
- GSE266422 Transcriptome profiles of wild-type, IRF8KO microglia 16 samples shares profiles, type
- GSE202232 Comparing transcriptional profiles of type 2 innate lymphoid cells from WT and Rag1 knockout mice 12 samples shares profiles, type
- GSE249704 Transcriptional profiles of tumor-draining lymph node resident CD11c+ cells in wildtype versus APOE-KO mice 12 samples shares profiles, type
- GSE2926 Gene Expression Profiles of Scd1 knockout mice vs wild type mice on chow diet: Liver. 10 samples shares profiles, type
- GSE288332 Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions. [ATAC-Seq] 18 samples shares cognition, type
- GSE241165 Characterizing the gene expression profiles of 4T1 and 4T1.2 cells at different stages of bone metastsis using SMART-Seq2 technology 1248 samples shares profiles
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.