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Single-cell RNA sequencing reveals recruitment of the M2-like CCL8high macrophages in Lewis lung carcinoma-bearing mice following hypofractionated radiotherapy

GSE256051 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/04/03 Platform GPL24247
Summary
Tumor-associated macrophages (TAMs) are a crucial factor in reprogramming the tumor microenvironment following radiotherapy. The mechanisms underlying this process remain to be elucidated. We used single cell RNA sequencing (scRNA-seq) to investigate the effects of hypofractionated radiotherapy on macrophages dynamics in a subcutaneous Lewis lung carcinoma (LLC) murine model.
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Single-cell RNA sequencing reveals recruitment of the M2-like CCL8(high) macrophages in Lewis lung carcinoma-bearing mice following hypofractionated radiotherapy
Yang H, Lei Z, He J et al. · Journal of translational medicine 2024 · PMID 38528587 · doi:10.1186/s12967-024-05118-6
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Also filed as BioProject PRJNA1077945 and SRA study SRP490306. Searching any of these in the dataset finder brings you back here.

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