GEO series
Neutral sphingomyelinase 2 inhibition alters inflammatory gene expression signatures in the brain of mice infected with West Nile virus
GSE256333
Mus musculus
Expression profiling by high throughput sequencing
27 samples
2025/07/16
GPL24247
Summary
To investigate the in vivo effects of DPTIP during WNV infection in a mouse model, we compared infected mice with WNV NY99 treated with DPTIP or vehicle and uninfected (mock) mice. DPTIP is a pro-dug that targets mouse nSMASE. We then performed gene expression profiling analysis using data obtained from RNA-seq from infected-vehicle mice, uninfected mice and infected DPTIP-treated mice
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Paper (PMID 40652589) ↗
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