Genomic Analysis of Human Brain Metastases Treated with Stereotactic Radiosurgery Reveals Unique Signature Based on Treatment Failure. [RNA-Seq]
RNA-seq (gene expression) · human · 46 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 46 samples: 41 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failureiScience · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE256463_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1079731 and SRA study SRP491372. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 46 sample titles: 41 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8098838 NU00570
- GSM8098839 NU00612
- GSM8098840 NU00617
- GSM8098841 NU00890
- GSM8098842 NU00913
- GSM8098843 NU01164
- GSM8098844 SR05_PR
- GSM8098845 SR7CR
- GSM8098846 SR7PR
- GSM8098847 SR08_PR
- GSM8098848 SR11CR
- GSM8098849 SR12_CR
- GSM8098850 SR12_PR
- GSM8098851 SR14_CR
- GSM8098852 SR14_PR
- GSM8098853 SR15_CR
- GSM8098854 SR15_PR
- GSM8098855 SR16_CR
- GSM8098856 SR16_PR
- GSM8098857 SR17_RF
- GSM8098858 SR18_CR
- GSM8098859 SR18_PR
- GSM8098860 SR19CR
- GSM8098861 SR20_RF
- GSM8098862 SR21_CR
- GSM8098863 SR21_PR
- GSM8098864 SR23_CR
- GSM8098865 SR23_PR
- GSM8098866 SR24_CR
- GSM8098867 SR25_CR
- GSM8098868 SR25_PR
- GSM8098869 SR26_CR
- GSM8098870 SR26_PR
- GSM8098871 SR28_CR
- GSM8098872 SR28_PR
- GSM8098873 SR29_CR
- GSM8098874 SR29_PR
- GSM8098875 SR30_CR
- GSM8098876 SR30_PR
- GSM8098877 SR31_CR2
+ 6 more — browse all 46 samples with per-sample file links →
- GSE328391 Airway immune signatures of protection and disease progression in recent human tuberculosis household contacts [bulk RNA-seq] 125 samples shares signature, rna-seq
- GSE330465 Gene expression profiling of neoadjuvant ABFOLFOX treatment in patients with unresectable colorectal cancer with liver metastases 104 samples shares metastases, treatment
- GSE290695 Identification of Crohn’s disease subtypes in single cell RNA sequencing signatures of treatment naïve samples across the gastrointestinal tract 95 samples shares signature, treatment
- GSE245414 RNA-seq profiling of breast metastases from different sites 42 samples shares metastases, rna-seq
- GSE273848 Definition of a multi-omics signature for Esophageal Adenocarcinoma prognosis prediction [totalRNA-seq] 40 samples shares signature, rna-seq
- GSE323965 Transcriptional signatures indicating RB function may predict response to CDK4/6 inhibition in endometrial cancer [RNA-Seq] 39 samples shares signature, rna-seq
- GSE339456 Integrated bulk and spatial transcriptomic analysis identifies progression-associated molecular signatures in biopsy-proven hypertensive nephropathy [RNA-seq] 35 samples shares signature, rna-seq
- GSE324453 Dissecting the cellular architecture of breast cancer brain metastases reveals prognostically distinct immune landscapes [snRNA-Seq] 28 samples shares metastases, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.