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ERG activates a stem-like proliferation-differentiation program in prostate epithelial cells with mixed basal-luminal identity [scATAC-seq]

GSE258962 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 7 samples Submitted 2025/04/07 Platform GPL24247
Summary
Performed scATAC-seq in 3 timepoints of an autochthonous mouse model. A proliferative population is characterized by an ERG-specific chromatin state enriched for NFkB, AP-1, STAT and NFAT binding, with implications for TF cooperativity. ERG is enriched in a small stem-like population implicates the chromatin context of these cells as a critical variable for unmasking its oncogenic activity.
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Also filed as BioProject PRJNA1080280 and SRA study SRP491659. Searching any of these in the dataset finder brings you back here.

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